Preventive chemotherapy
WHO recommends preventive chemotherapy as the core strategic intervention against four main helminth diseases: lymphatic filariasis, onchocerciasis, schistosomiasis and soil-transmitted helminthiases. Preventive chemotherapy is also a component of the SAFE (Surgery, Antibiotics, Facial cleanliness and Environmental improvements) strategy for the control, prevention and elimination of trachoma. It is recommended also for controlling morbidity due to foodborne trematode infections, and is a strategic component of WHO-recommended strategies against leprosy, scabies, taeniasis and yaws.
Medicines are generally delivered and administered to entire eligible populations or population groups mostly by non-medical personnel following a short training session. Schools, community networks and other social platforms are extensively used as outreach points to maximize coverage.

A child receives the proper dosage of Zithromax during a treatment campaign for trachoma in Mozambique.
Resources
Key publication
Preventive chemotherapy: tools for improving the quality of reported data and information:...
Latest publications
All →This revision and update of the 2011 guidance includes a new mapping protocol, adapted from the TAS, as a practical tool for determining when MDA is...
Global update on implementation of preventive chemotherapy against neglected tropical diseases (NTDs)...
Summary of preventive chemotherapy (PC) in 2023 PC is defined as large-scale delivery of safe, single-administration, quality-assured medicines, either...
Human infection with schistosomes and soil-transmitted helminths is the cause of clinical morbidity in many areas of the world. Human schistosomiasis...
Tools
Disease specific request forms for selected PC medicines
Foodborne trematode infections
Related activities